NIRT

National Institute for Research in Tuberculosis
No.1, Mayor Sathiyamoorthy Road
Chetpet, Chennai 
600 031, India
91-44-2836 9500 
www.nirt.res.in 

  • Established in 1956 as India’s Tuberculosis Research Centre
  • Internationally renowned TB research institution, Supranatural Reference Laboratory, and WHO Collaborating Centre for TB Research and Training
  • CIDI research partnership looking at:
    • Lasting pulmonary effects and respiratory impairment following recovery from TB
    • Improving TBM treatment outcomes in children ages 6 months to 12 years
    • Assessing dosage levels of rifampicin and evaluating safety of TBM treatment
    • Relationship between diet and inflammation during pregnancy
    • Immune changes that happen during pregnancy and how they affect different methods for latent TB screening among pregnant women
    • Host and microbial factors associated with 1) poor response to TB treatment, 2) progression to active TB disease and 3) TB transmission/acquisition

Inflammation in HIV-infected Pregnant Women: Relationship with Diet, Gut Microbiome and Preterm Birth

Post Date: 
2014-10-28
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
NIRT
This study was terminated May 7, 2018. P regnancy is a state of relative immunosuppression in order to protect the fetus from being rejected. It has also been shown that the Th-1 helper cell response, which is normally necessary for overcoming TB infection...

Diagnosis of Tuberculosis Infection and Th1 Immune Response in Pregnant Women in India

Post Date: 
2014-09-01
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
NIRT
This study was terminated April 16, 2018. Tuberculosis (TB) disease is a major cause of mortality among Indian women of reproductive age; approximately 20-50% of women in India are latently infected with Mycobacterium tuberculosis (MTB). Due to immune...

Impact of Immune Changes of HIV and Stages of Pregnancy on Tuberculosis

Post Date: 
2014-09-01
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
NIRT
This is the Parent Study for CCGHE’s PRACHITI (PRegnancy And CHanges In TuberculosIs) effort. It's supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development at the U.S. National Institutes of Health. Purpose: TB is a...

Optimizing Treatment to Improve TBM Outcomes in Children

Post Date: 
2014-05-01
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
NIRT
This study, known as TBM Kids, is being conducted in India and Malawi. Primary Objectives To characterize the pharmacokinetics (PK) (plasma and cerebrospinal fluid (CSF)) of rifampicin given at model-derived optimal daily doses and...

Tuberculosis Noon Conference

Post Date: 
2013-10-24
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
DY Patil
Hinduja Hospital
NIRT
This effort ended in 2015. As part of the BJGMC-Johns Hopkins India Fogarty Training Program, from 2013-2015 CCGHE hosted the live Tuberculosis Noon Conference webcast. Led by Drs. Maunank Shah, Jonathan Golub, and Richard Chaisson, these webcast meetings brought together Johns Hopkins TB...

Cohort for Tuberculosis Research by the Indo-US Medical Partnership (C-TRIUMPH)

Post Date: 
2013-09-28
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
NIRT
Collaboratively funded by the US NIH, India’s Department of Biotechnology [DBT], and Indian Council of Medical Research, the Cohort for TB Research by the Indo-US Medical Partnership (C-TRIUMPH) is an Indo-US research consortium that is part of RePORT India, a countrywide consortium for TB...

RePORT India

Post Date: 
2012-06-30
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Hinduja Hospital
NIRT
RePORT India is a joint venture between the Indian and US governments. The Indo-US Vaccine Action Program, a collaboration between the Indian Department of Biotechnology (DBT), the Indian Council of Medical Research (ICMR), and the US NIH, is co-funding six teams of India- and US-based...

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