Rahul Lokhande, MD: Pulmonary Medicine

Pune, India
Role: 
Scholar
BJGMC-JHU Fogarty HIV-TB Program Trainee

Education:
MBBS, BJ Government Medical College, Pune, 1997
MD, BJ Government Medical College, Pune, 2000. (Pulmonary Medicine), from Pune University, Maharasthra.
Dr. Rahul Lokhande, At Present working as Associate Professor in Department of Pulmonary Medicine,

Overview:
He is Unit In charge at BJ Government Medical college and Sassoon Hospital Pune . He has special Interest in Bronchoscopy and Respiratory Intensive Care Unit of Sassoon Hospital. As a part of BJMC-JHU Fogarty Training Program HIV –TB Primary Drug he is interested in investigating drug-resistant tuberculosis in normal and immunocompromised patients. He trained as trainer of DOTS and DOTS Plus program under the RNTCP. He has also worked with National Aids Research Institute for their trial in B.J. Government Medical College.

Faculty Mentor(s): 
Bob Bollinger, MD, MPH
Amita Gupta, MD, MHS

Assessing prevalence and risk of lung morbidities including lung nodules and cancer using non contrast CT among PLHIV in Pune, India

Post Date: 
2022-11-25
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Primary objective Determine the prevalence of pulmonary nodules, including lung cancer using NCCT. Determine the risk of pulmonary nodules, including lung cancer using NCCT. Evaluate the association of smoking, immune suppression, ART, and TB with the prevalence and risk of NCCT-diagnosed pulmonary...

Inflammasome Genetics and Tuberculosis Treatment Outcomes

Post Date: 
2019-11-07
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
NIRT
Dr. Amita Gupta is a Co-PI on this study. STUDY DESIGN We will conduct a retrospective case-cohort study nested within the CTRIUMPH and EDOTS cohorts to address our study objectives. This will enable us to measure the association of polymorphisms with multiple clinical outcomes simultaneously and...

Predictors of Resistance Emergence Evaluation in Multidrug Resistant-Tuberculosis Patients on Treatment (PREEMPT Pilot Study)

Post Date: 
2018-03-20
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Hinduja Hospital
NIRT
Indo-JHU Clinical Resarch Partnership is participating with Brazilian colleagues in a 3-year effort led by Boston University to identify what contributes to TB drug resistance.

Risk Factors for Unfavourable Treatment Outcomes among Multidrug-Resistant Tuberculosis Patients in Public Sector Treatment in Pune

Post Date: 
2017-03-29
   |   
Countries: 
India
This study is funded and conducted under the U.S. National Institutes of Health, Fogarty International Center. This study seeks to identify risk factors associated with unfavourable treatment outcomes (death, treatment failure, default, XDR-TB) among multidrug-resistant...

Characterising cause of death among people treated for drug-susceptible TB in India

Post Date: 
2023-01-12
   |   
Countries: 
India
Publication: 
The International Journal of Tuberculosis and Lung Disease
Annually, 1.5 million people die of TB.1 India has thehighest burden of TB,1 and in 2020, the case fatality ratio (CFR) among people with drug-susceptible TB was 4.3%.2 Even after treatment, mortality is more than two-fold higher among people with prior TB compared to the general population.3...

Clinical and Immunological Markers of Pulmonary Impairment among People Living with HIV in India

Post Date: 
2022-05-11
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Publication: 
Open Forum Infectious Diseases
Background Despite antiretroviral therapy, chronic lung diseases remain an important source of morbidity and mortality in people with HIV (PWH). We sought to identify clinical and immunological markers of pulmonary impairment among PWH in India. Methods Two hundred ten adult PWH receiving...

Diabetes Mellitus and Tuberculosis Treatment Outcomes in Pune, India

Post Date: 
2021-04-01
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Publication: 
Open Forum Infectious Diseases
Background Diabetes mellitus (DM) increases the risk of tuberculosis (TB) disease. Knowledge of the impact of DM on TB treatment outcomes is primarily based on retrospective studies. Methods We conducted a prospective cohort study of new pulmonary TB patients with and without DM (TB-DM and TB only...

Tuberculosis preventive treatment should be considered for all household contacts of pulmonary tuberculosis patients in India

Post Date: 
2020-07-29
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Publication: 
PLoS One
PLoS One: Dr. Mandar Paradkar and colleagues conducted a CTRIUMPH study that supports TB preventive therapy for all household contacts of pulmonary TB patients in India

Delays and barriers to early treatment initiation for childhood tuberculosis in India

Post Date: 
2019-10-01
Publication: 
International Journal of Tuberculosis and Lung Disease
BACKGROUND: India accounts for 27% of global childhood tuberculosis (TB) burden. Understanding barriers to early diagnosis and treatment in children may improve care and outcomes. METHODS: A cross-sectional study was performed among 89 children initiated on anti-TB treatment from a public hospital...

Assessment of lung function in successfully treated tuberculosis reveals high burden of ventilatory defects and COPD

Post Date: 
2019-05-23
   |   
Countries: 
India
Publication: 
PLoS One
New in PLoS One: We found a high burden of lung function defects and COPD in tuberculosis cases who successfully completed treatment, suggesting a need for lung function screening as part of patient management.

Respiratory health status is associated with treatment outcomes in pulmonary tuberculosis

Post Date: 
2019-04-19
   |   
Countries: 
India
Publication: 
The International Journal of Tuberculosis and Lung Disease
BACKGROUND: The association between respiratory impairment and tuberculosis (TB) treatment outcomes is not clear. METHODS: We prospectively evaluated respiratory health status, measured using the Saint George's Respiratory Questionnaire (SGRQ), in a cohort of new adult pulmonary TB cases during and...

Barriers to screening and isoniazid preventive therapy for child contacts of tuberculosis patients

Post Date: 
2018-10-01
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Publication: 
International Journal of Tuberculosis and Lung Disease
Universal, timely TB screening and IPT for exposed children are urgently needed to reduce pediatric TB in India

The effect of diabetes mellitus on the pharmacokinetics and pharmacodynamics of tuberculosis treatment

Post Date: 
2018-08-20
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
DY Patil
NIRT
Publication: 
Antimicrobial Agents and Chemotherapy
DM and higher HbA1c increased the risk of not achieving therapeutic targets for pyrazinamide, but higher pyrazinamide concentrations were asociated with worse microbiologic and clinical outcomes

Trends in HbA1c levels and implications for diabetes screening in tuberculosis cases undergoing treatment in India

Post Date: 
2018-07-01
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
DY Patil
Publication: 
International Journal of Tuberculosis and Lung Disease
SETTING: The optimal timing of screening for diabetes mellitus (DM) among tuberculosis (TB) cases is unclear due to the possibility of stress hyperglycemia. DESIGN: We evaluated adult (18 years) pulmonary TB cases at treatment initiation as well as at 3 months,...